Closing the loop on the gut.
REAL-TIME MOTILITY & CHEMISTRY SENSED IN-VIVO, MODELED AS A DIGITAL TWIN
All health and disease starts in the gut — yet it's the last open-loop system in the body. GutOS is the closed-loop infrastructure powering every Gut Intelligence application, from GLP-1 tolerability to precision nutrition.
The gut is the body's
last open loop.
More than 90% of chronic medications, every nutrient and every supplement passes through the gut. Yet there is no real-time feedback from inside it. Stool and microbiome tests are downstream snapshots. Wearables only watch the cardiovascular system. No one can see what's actually happening to motility and chemistry, in the moment, segment by segment.
The closed-loop layer for Gut Intelligence.
Like NVIDIA powers the AI stack, GutOS powers the Gut Intelligence stack. An ingestible GutSensing Capsule streams the universal signals of motility and chemistry — the balance of protons and electrons in each segment of the gut. A Digital Gut Twin learns each user's personal baseline, and GutOS routes the closed-loop insights into any downstream application: therapeutics, nutrition, supplementation, diagnostics.
VALIDATED AND BUILDING WITH WORLD-CLASS RESEARCH INSTITUTIONS
Real-time. Proactive. At-home.
No clinics. No invasive procedures.
Personal gut data - delivered at the right moment.
Swallow GutSensing Capsule
Users swallow a disposable vitamin-sized capsule. It safely travels the gut throughout one digestive cycle and wirelessly transfers unique gut data to user's phone and care provider's dashboard, currently captured via a wearable device.
Digital Gut Twin emerges
Your digital twin learns your gut's 'baseline' fingerprint and detects deviations. A living model of your individual gut improves with each capsule, surfacing early instability signals before distress escalates and simulating personalized dosage and lifestyle impact.
Proactive Care Provider
Clear, non-clinical outputs supporting GLP-1 care providers when personalizing GLP-1 dosing and lifestyle support to protect GLP-1 retention.
Our first beachhead: GLP-1 tolerability.
GLP-1 receptor agonists work — but 65% of weight-loss users drop out in year one, mostly from motility-driven nausea, vomiting, diarrhea and constipation. GutOS turns the gut into a measurable signal across the full GLP-1 lifecycle: early tolerability detection, responder selection, and cessation support through endogenous GLP-1 modulation.
Contact us to collaborateCatch the motility shifts that precede nausea, vomiting and constipation — before patients abandon therapy.
Objective gut readouts surface who responds, who needs titration, and who needs a different protocol.
Modulate gut chemistry through diet and lifestyle to support endogenous GLP-1 activation after the drug.
We ship the GutSensing Capsule to users' homes — the first at-home gut data channel for telehealth programs.
Real science.
Safe capsule.
Right timing.
- ★
- IPExclusive imec patent and deeptech knowhow
- 75+Capsules ingested across 20 human subjects
- ✓Demonstrated capsule safety & ingestibility
- 3+Paid pilots with public clinics
- 2LOIs signed with GLP-1 care providers
NVIDIA built the infrastructure for AI.
We're building it for Gut Intelligence.
Today the beachhead is GLP-1 tolerability. Tomorrow it's every chronic medication, every supplement, every nutrition decision and every metabolic, longevity and preventative care app — all running on top of a closed-loop gut data layer.
Currently sold for research trials EU. Fundraising Seed. Let's talk.
We're meeting mission-aligned investors and collaborators who understand the importance of the gut for overall health, the promise of GLP-1 as a reset and digital twins as a personal model. Working with the best experts on this. Speak to you soon, Astrid Hart de Ruijter Founder & CEO GutOS